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Horgen/Schlieren, ZH — CDR-Life announces a novel drug candidate for the treatment of axial spondyloarthritis. This chronic inflammatory rheumatic disease, also known as ankylosing spondylitis, can be largely controlled with treatment, but there is currently no cure.
(CONNECT) CDR-Life has announced a new candidate for its M-gager antibody technology platform. According to a press release, the drug in question is CDR209, a novel T-cell engager for the treatment of axial spondyloarthritis. T-cell engagers are a class of engineered bispecific monoclonal antibodies that are currently being studied as anticancer agents. If the new candidate proves effective, it would be “an important step toward expanding our M-gager platform to autoimmune diseases,” CEO Dr. Christian Leisner is quoted as saying. The new drug candidate thus complements the oncology portfolio of the biotech company, which is a member of the Bio-Technopark Schlieren-Zurich. Its anti-cancer candidate, CDR404, is currently in a Phase 1 clinical trial.
Axial spondyloarthritis is better known in German-speaking countries as Morbus Bechterew. This chronic inflammatory disease primarily affects the spine and the sacroiliac joints. It is typically accompanied by back pain, limited range of motion, and possible stiffness in these joints. In the U.S. alone, an estimated 2.7 million adults are affected. It is true that treatment options have improved in recent years. However, according to the statement, many patients are still unable to adequately manage their condition.
On its M-gager platform, CDR-Life has now developed CDR209, a candidate that targets TRBV9-positive T cells. These specific T cells appear to play an important role in the immune response in many patients. In preclinical studies, CDR-Life has reprogrammed healthy T cells to selectively eliminate these TRBV9 T cells without attacking other cells.
“The selective removal of these cells while preserving the rest of the immune system opens up the possibility of interrupting the disease process at a more fundamental level,” said Denis Poddubnyy, professor of internal medicine and director of the Division of Rheumatology at the University of Toronto’s Temerty Faculty of Medicine. "In the long term, the goal is to determine whether such an immunological reorientation can lead to sustained disease control or even to remission without the need for treatment."
Founded in 2017, CDR-Life AG is headquartered in Horgen and is a member of the Bio-Technopark Schlieren-Zurich. ce/mm

Ankylosing spondylitis mainly affects the spine and the sacroiliac joint. Stock image: Pexels
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Zurich/Affoltern am Albis, ZH/Traunreut — At the new Movecity multisport arena in Affoltern am Albis, ASB’s digital LED glass floor is now permanently available to a wide audience for the first time. The Arena by ASB GlassFloor can be booked for various sports, games, and events.
(CONNECT) The Arena by ASB GlassFloor is part of the new Movecity multisport arena at Moosbachstrasse 13 in Affoltern am Albis. Until now, digital sports flooring has been used primarily in professional venues and at major sporting events, such as at FC Bayern Basketball’s BMW Park in Munich. According to a press release, the LED glass floor from ASB Systembau Horst Babinsky GmbH, based in Traunreut, Bavaria, is now available for booking by the general public for the first time.
The ASB GlassFloor is controlled via a software platform and can be programmed for a variety of uses. For example, field markings for various sports, as well as animations, graphics, logos, and live data, can be displayed directly on the 28-by-15-meter surface. A tracking system also enables interactive games in which participants control what happens on the floor through their movements.
The arena can be booked by individuals, groups, clubs, schools, and businesses. In addition to recreational sports, events, workshops, and corporate functions are also possible. It is operated at Movecity as a shop-in-shop by Zurich-based Athlete World GmbH in collaboration with Zug-based ASB Arena & Event Services AG (AES), a subsidiary of ASB.
movecity ag held its official opening weekend in early September. Spanning just under 13,000 square meters, the facility brings together ten sports and activity areas. These include a trampoline park, a zipline, courts for padel and pickleball, a freestyle park for skateboarding, BMX, mountain biking, and scooters, as well as activities for freerunning and rock climbing. ce/as

Thanks to the glass floor, pitch markings for various sports, as well as animations, graphics, logos and live data, can be displayed directly on the 28-by-15-metre surface. Stock image: Sayeed Chowdhury/Pexels
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Schlieren, ZH/Lausanne — Corintis from Ecublens, VD, has won the Top100 Swiss Startups competition for the second year in a row, followed by DeepJudge from Zurich and PAVE Space from Villeneuve, VD. The best robotics startup of 2026 is Flexion Robotics from Zurich, ranked 6th. Memo Therapeutics from Schlieren, ZH, recorded the largest exit.
(CONNECT) At the awards gala on September 9, 2026, the Gold Award for the Top 100 Swiss Startups 2026 went to Corintis, just as it did last year. Founded in 2022 as a spin-off from the Swiss Federal Institute of Technology in Lausanne (EPFL) by Remco van Erp and Sam Harrison, this engineering startup is developing microfluidic cooling technology for high-performance chips used in data centers.
More than 100 jury members awarded the Silver Award to DeepJudge from Zurich. The core product of the legal tech company founded in 2022 by CEO and co-founder Paulina Grnarova, which emerged from the Swiss Federal Institute of Technology in Zurich, is a proprietary artificial intelligence system. It can highlight a law firm's expertise, which is based, among other things, on documents, strategies, and precedents.
PAVE Space (Villeneuve, VD) received the Bronze Top 100 Award. Founded in 2023 at EPFL, the spin-off of the student-led and co-founded Gruyère Space Program is developing the Kickstage spacecraft. It can transport satellites from low Earth orbit to their final destination in a matter of hours rather than months.
In addition to the main prizes, special awards were also presented in six categories. The top newcomer is Dexterous Endoscopes (Epalinges, Vaud), the only company in the top 100 founded in 2026. The largest round of financing, totaling $225 million, went to Kandou Bus (Saint-Sulpice, VD).
In 2026, Memo Therapeutics (Schlieren, ZH) recorded the largest exit, with an estimated value of over 700 million. The highest-ranked biotech startup is Aukera Therapeutics (Saint-Sulpice). The best cleantech startup is Voltiris (Epalinges). And Flexion Robotics (Zurich) was named the best startup in robotics.
“The founders featured in this year’s Top 100 are tackling some of the most important challenges facing our world,” says Stefan Steiner, program director of the event—also known as the “Oscars of Swiss Startups”—in a press release. "Their ambition, combined with Switzerland's unique strengths in research, engineering, and entrepreneurship, is helping to build the next generation of global market leaders."
The competition is organised by the "Handelszeitung" and Venturelab. Over the course of its 16-year history, 677 high-tech startups have been honored. Together, they raised 18.8 billion francs in venture capital and created 27,288 jobs. 111 of the companies successfully exited, 11 became unicorns, and another 11 are now publicly traded. ce/mm

DeepJudge, based in Zurich, has come second in the top 100. Image: Courtesy of Venturelab
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We asked Simona Fehlmann, CEO and co-founder of sallea, what innovation means to her. Sallea manufactures 3D-printed salt templates that enable the production of lighter and stronger carbon components.
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From 2024 to 2026, five AI projects were successfully implemented in the second implementation phase of the Innovation Sandbox for AI: AI in medical documentation, autonomous inspection robots, digital eye clinic, sensor-based bridge monitoring and AI for building permits. As artificial intelligence is becoming increasingly important for companies and society, the Innovation Sandbox will begin its third implementation phase this year. Together with partners, further AI projects are tested under real conditions and open regulatory issues are clarified.
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We asked Richard König, Deputy Head of Legal and Construction at Gossweiler Ingenieure AG, what innovation means to him. Gossweiler is an engineering company that offers consulting, planning and construction as well as analyses, measurements and tests in various areas. Its services are geared towards cities, municipalities, community-based businesses, companies and private individuals.
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Under the patronage of the Obersee-Linth regional management, the canton of Glarus, Schwyz Next, Standortförderung Zürioberland, Impulsort and Wirtschaftsförderung Höfe OST organizes innovation conferences on various topics several times a year.
Detailed information can be found at the respective events, see link to the website.
Participation in the events is generally free of charge.

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Taste, smell, discover: Startups, farmers, companies, and projects are opening up their world and inviting you to experience the future of food firsthand—from regional circular economies to alternative ingredients and new crops. You can sample some things right away, take a lot of them home, and experience it all.
Come on by to taste and shape your own future when it comes to healthy and sustainable eating in everyday life!

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INNOVATE Bau- PIONEERS.BAUEN.ZUKUNFT.
INNOVATE Bau is not a traditional conference, but a co-creation platform for applied innovation in the construction industry. INNOVATE Bau creates an environment in which new partnerships are formed, innovations are accelerated and concrete projects are initiated. INNOVATE Bau stands for sustainable construction – socially, economically and ecologically compatible.
What sets INNOVATE Bau apart:
– 30 Interactive sessions: Participate instead of just listening
– Co-creation formats: Developing content together instead of consuming it
– Practice-oriented innovation: focus on transfer to real projects
– Targeted networking: matchmaking & speed dating for new partnerships
– Makers’ Zone: experience solutions, prototypes and start-ups live
– Innovate Magazine: Comprehensive magazine with background reports, facts and interviews
Organized by Switzerland Innovation Park Central and Empa NEST.

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Researchers from the University of Zurich and ETH Zurich are conducting a pioneering study examining how different organisational arrangements shape individuals’ willingness to share knowledge in the age of AI and invite organisations to participate.
The Swiss economy is losing valuable critical knowledge every year as experienced professionals retire or leave their companies. That knowledge is the operational intelligence required for AI transformation to succeed. Switzerland competes on expertise, precision, institutional continuity and not cost. As Baby Boomers approach retirement they will be participating in knowledge handover activities and letting that expertise retire without capture is a threat to the foundation of its economic advantage.
Researchers from the University of Zurich and ETH Zurich are conducting a pioneering study examining how different organisational arrangements shape individuals’ willingness to share knowledge after retirement.
THE STUDY – From Experience to Organisational Memory : An Experimental Vignette Study on Tacit Knowledge capture in Late-Career Transitions – forms part of project – Silver AI, an AILAS applied research initiative exploring the human side of AI-assisted knowledge retention and translating research insights into practical systems for organisational memory.
The study is supported by the Digital Society Initiative, UZH.ai, the Data Innovation Alliance and Industry Partners.
Swiss organizations with more than 150 employees are invited to participate or sponsor and help shape practical frameworks for Al-assisted knowledge retention. Participating companies receive benchmarked survey results, early access to findings, and priority access to pilot programs.
Founder / Researcher
Janmejay Singh
janmejay@ailas.ch
+41783306975

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Blockchain is much more than Bitcoins and offers advantages for many industries. Since the introduction of blockchain in 2009, the technology has continued to develop. Nevertheless, discussions about the possible uses of blockchain continue to be heavily influenced by cryptocurrencies, and since 2021 also by so-called non-fungible tokens (NFT). The result: confusion around blockchain and its potential are equally great.
Blockchain technology offers a suitable technical basis for securely digitising and automating business processes, collaborating efficiently and creating more robust digital infrastructures. This can also open up new business areas. In order to exploit this potential, leaders need to move away from hype, but also from blanket criticism. This study aims to be a starting point for this.
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Economic growth in the canton of Zurich – increasing prosperity and quality of life while reducing environmental pollution. This is the conclusion of the latest economic monitoring by the Office of Economic Affairs. Economic growth in the canton of Zurich in recent years has not only increased disposable income, but also enabled a better quality of life, such as leisure, education and health. In addition, environmental pollution has decreased in many areas. A thought experiment also shows that zero growth would lead to many problems.
The economic development of the Canton of Zurich is remarkable: the gross domestic product (GDP) has more than doubled in the last 40 years after adjusting for inflation. - from CHF 74 billion to CHF 159 billion. On a per capita basis, economic output rose from CHF 65,000 to CHF 101,000 - and the majority of this increase in value added was paid out to the people of Zurich in the form of higher wages. However, they not only achieved higher incomes, but also more free time: the number of hours worked per capita has fallen by almost half an afternoon per week since 1991. As a result, the prosperity of the people of Zurich has steadily increased. The driving force behind this development was and is technological progress and innovation.
However, economic growth entails more than just rising monetary income and more leisure time. Tax revenues have also risen in the canton of Zurich - as has the quality of life in many areas. The factors that influence the quality of life can be perceived very differently from person to person. With the "Regional Well-Being Indicators" and the "Better Life Index", the OECD has established a system for measuring quality of life. Various indicators are shown on the basis of eleven categories, providing a comprehensive picture of quality of life and its components.
Improvements in the canton of Zurich can be seen in particular in the areas of education (increase in the level of education and the rate of further education), employment (fall in unemployment and increase in the employment rate), work-life balance (increase in the part-time rate and reduction in hours worked per capita), health (increase in life expectancy and expansion of healthcare) and technology (internet access). The results are mixed in the area of safety (decrease in the number of violent crimes per capita, but slight increase in traffic accidents per capita) and in the area of housing (decrease in the average housing cost burden, but stagnating satisfaction with the housing situation). Finally, the subjective life satisfaction of the people of Zurich has remained largely the same but at a very high level.
It is undisputed that economic growth in the past was often associated with an increasing demand for resources and that a high level of prosperity in almost all countries goes hand in hand with a significantly larger ecological footprint. However, this is not a law of nature, as a look at the statistics shows: Over the last thirty years, economic growth, resource consumption and environmental pollution have been decoupled, especially in richer countries. This also applies to the canton of Zurich: while real GDP has risen by 69% since 1990, the quality of the environment has improved in most cases. This applies, for example, to material consumption, the recycling rate, air and water quality and the overall environmental footprint. No absolute, but at least a relative decoupling has so far been observed in the quantities of waste, soil sealing and certain biodiversity indicators.
The decoupling is also clearly visible in the currently most important indicator, greenhouse gas emissions. While the economic growth achieved on Zurich soil has risen steadily, the GHG emissions generated here have fallen by around 17% since 1990. However, this consideration only includes the so-called "white" emissions - i.e. those that are emitted in the country itself. If emissions caused by the production and transportation of goods imported from abroad are also included, greenhouse gas emissions have fallen less sharply over the last 30 years, but they have also decreased. Either way, achieving the Paris climate target remains a major challenge despite decoupling.
But what would be the impact on prosperity, society and the environment if the Zurich economy were to stop growing? To this end, the INFRAS research office has modeled a thought experiment in economic monitoring up to the year 2050 - not in the sense of a forecast, but as an illustrative scenario. This shows that zero growth would lead to significantly lower incomes and an increased risk of poverty. At the same time, the financial challenges would become greater: there would be much less tax revenue and money available for social security than in a growing economy, which would lead to distribution conflicts. Environmental quality would improve in some areas, but at a high price. In addition, fewer financial resources would be available for environmental protection.
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Digital Documentation. Maturity model in long-term care using the example of selected Swiss care facilities. Potentials of administrative relief, quality assurance and cost reduction.
Background: Digital nursing documentation, as an essential part of the
electronic patient dossier, especially the planning and documentation of
Measures for the care of persons in need of care as well as their accounting, but also the organization of work processes and rostering of caregivers. The occupational exit rate is 21.9% (Merçay et al., 2021). Often the
administrative effort and time pressure were cited as reasons for leaving. Target: Carers
should be sustainably relieved by further digitization steps. A
Maturity determination enables further development steps. Method: The study was conducted in a cross-sectional design and targeted medium and large long-term care institutions in German-speaking Switzerland. Data were collected via online questionnaire at the end of 2021 with a pre-determined sample size, for validity and reliability. It was possible to evaluate 53 responses. Results: In addition to the quality assurance aspects of maturity assessment, impacts on the core care process were evident. After digitization, the administrative effort of nursing documentation could be quantified as 65 minutes less per eight-hour shift. Conclusion: By expanding the relief opportunities that present themselves, the workload for the workforce can be significantly reduced. In the context of corporate and cultural change, the results led to promising recommendations for action in everyday care.
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